• Io Sapsai 🌱@lemm.ee
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      1 month ago

      Eh one every now and then is fine, I take it for motion sickness when going on long car rides. Half a pill is enough. Then again, taking enough to get nightshade-like poisoning is really not recommended.

      • candyman337@sh.itjust.works
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        1 month ago

        Long term use has now been linked to neurological issues, it crosses the blood brain barrier. However, yes occasional use is relatively safe. But it is not recommended as a daily antihistamine at all these days.

      • swab148@lemm.ee
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        1 month ago

        Can you expand on that? I take melatonin every day, have I been poisoning myself?

        • Kraven_the_Hunter@lemmy.dbzer0.com
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          1 month ago

          It’s more of a placebo than an actual sleep aid. It’s not harmful though. If you want to take it, don’t worry. If you think it helps, then in some small way it does.

        • meowMix2525@lemm.ee
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          1 month ago

          I’ve heard of people developing a dependence on it when taking it regularly. Especially kids.

          I use it a couple times a year for the occasional restless night and it seems to work for me.

          It’s not inherently harmful afaik but it could disrupt your sleep if for any reason you have to stop taking it.

        • dmMeYourNudes@lemmynsfw.com
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          1 month ago

          It’s most useful to take 2-3 hours before bed to reset your circadian rhythm. Essentially it mimics the melatonin you make at sun down to prepare your body for sleep. You only need 1-2 mg to do this.

          • JoeBigelow@lemmy.ca
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            1 month ago

            I even think 1 mg is too much. It’s active in microgram doses. Also read the Wikipedia page, it’s poorly regulated and pills can contain upwards of 4x what they say.

      • Madison420@lemmy.world
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        1 month ago

        25, also don’t. It’s legit one of the craziest trips I’ve ever had and it’s highlighted by the fact that nearly everyone that does it will tell you it was crazy and powerful but don’t do it.

        No one should spend multiple hours having full on conversations with people that aren’t there, it’s deeply unpleasant to watch from the outside and I’ve been on both sides.

  • southsamurai@sh.itjust.works
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    1 month ago

    Well, here’s some personal experience.

    Back in my teens, I had a nasty bout of sinus issues, stemming from allergies.

    This was in the late eighties, and Benadryl was pretty much what everyone had. It was the default antihistamine.

    So, with my dad at work, and my mom needing to handle shit, I just grabbed some supplies and holed up in my room.

    Took a dose and then napped. Woke up, took the next dose, napped again.

    This cycle continued for two days. Or so I thought.

    I woke up at one point with he-man leaning out of the screen of the TV and talking some crazy shit. The walls were breathing, and the rug on the floor was crawling away.

    Now, I don’t know how long I lay there just watching everything wiggle and squirm into and out of other dimensions, but my mom got home and brought me the drink I had asked for. She had left about three hours before.

    To my best estimate, I took something like eight or ten of the damn things. I know I took at least six. There were two pills to a dose, and I could remember taking three doses for sure, but there were five of the blister packs empty, one of which might have been taken by my dad the week before, nobody could remember if it was from that box or the other we had. During all the dosing and sleeping, I thought it was days, and that makes the five doses a decent likelihood.

    It was. . . Interesting.

    For several days, I was loopy as hell. Not high, just kinda floating through life. And my dreams were even crazier than usual (I’ve always had intense dreams, still do) for about a week

    Benadryl and wu-tang have that in common, they ain’t nothing to fuck with.

  • ✺roguetrick✺@lemmy.world
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    1 month ago

    Here’s the nursing school pharase for anticholinergic side effects: Can’t see, can’t pee, can’t spit, can’t shit. Doctors tend to use: red as a beet, dry as a bone, blind as a bat, mad as a hatter, hot as a hare, full as a flask.

    If going through that just to also be able to hallucinate sounds appealing to you, go for it.

    • shneancy@lemmy.world
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      1 month ago

      just eat some psychedelics like a normal person the worst those can do is shatter your image of self and then rebuild it, oh and sometimes your muscles can ache a little afterwards because flexing them felt amazing

        • Zoboomafoo@slrpnk.net
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          1 month ago

          As an alternative to psychedelics, you can reach the same states through meditation. With modern techniques you won’t even need to sit under a tree for 49 days.

          • shneancy@lemmy.world
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            1 month ago

            technically you can but that’s going to take you roughly 100 times longer and might not work at all

            • Zoboomafoo@slrpnk.net
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              1 month ago

              My personal advice is: Making meditation a habit is the main hurdle. Set the bar of success so low you can trip over it, such as “I will meditate at least 3 minutes a day”.

              And for more what you seem to be after, you can’t go wrong with the Gateway tapes. They’re some guided meditations with a fancy audio technique that helps your brain tune to the desired mental frequency. This is a good place to start: r/gatewaytapes/wiki/start but I wouldn’t recommend browsing the subreddit unless you want your experience to be influenced by the sub’s communal lore.

              If you’d like I can send you a link to a drive folder with the files if you don’t want to pay.

      • ✺roguetrick✺@lemmy.world
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        1 month ago

        I think it should be pointed out that some traditional psychoactive drugs (such as datura) work the same was (they’re potent anticholinergics) and you’d have to be nuts to use them.

        • DogWater@lemmy.world
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          1 month ago

          Yeah I looked into mushrooms until I realized that people on SSRI meds won’t get anything from it and also seraronin sickness is lethal in some cases.

          • meowMix2525@lemm.ee
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            1 month ago

            The only time I’ve heard of serotonin syndrome being a real (common) risk is with MAOIs and alcohol…

            Shrooms/SSRIs causing it is not something I’ve ever been able to find information about. Every time I try to dig something up, because I am pretty careful about mixing drugs, the vague consensus (that is, in sources that aren’t making blanket statements about recreational drugs in general being bad because drugs are bad) is it’s probably fine, maybe it lessens the trip altogether, maybe it lessens the negative side effects of the trip, we just need to look into it more. Serotonin syndrome is a conspicuous thing to not mention if that’s a risk with any significant merit to it.

            It’s certainly an emerging field due to psilocybin’s place on the drug schedule preventing any very extensive research. It seems to me like that claim is based mostly on conjecture that because they both can increase presence of serotonin, that has potential to become a risky situation with SSRIs. Mind you, however, that the exact mechanisms of this are not fully understood by science and so aren’t very good bases to draw sweeping conclusions from without research or data.

            I’m both an SNRI user (strattera) and occasional psychonaut (not more than once a month, if I had to give an average for the year). I’ve never had anything but positive experiences with mushrooms and haven’t noticed any difference on vs off my SNRI.

            Had a bad trip on acid once but that was more down to hubris than anything else. I wasn’t even on the SNRI back then.

            This is of course anecdotal so absolutely take in all the information and make your own decisions for your body. Just thought I’d share what I know.

            (Sorry for all the edits, my longer comments tend to be living documents for their first 10 minutes of life or so, mostly for grammar fixes)

  • TootSweet@lemmy.world
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    1 month ago

    Because that shit will fuck you up. For life. It’s scary how so many of the really dangerous recreational drugs are so easily available while the arguably-less-harmful (and, yes, all drugs have potential for harm) are completely illegal.

    • meowMix2525@lemm.ee
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      1 month ago

      My buddy told me about how his dad found this energy supplement next to the dick pills at a gas station, said ‘what the hell, why not’ and it made him feel really weird and gross, which took him by total surprise, and he had to pull over to avoid causing an accident because he was driving.

      It was kratom. They sell kratom as an energy supplement at gas stations next to the dick pills. With no warning of the addiction or withdrawal symptoms associated with it being similar to that of opioids. He’d never even heard of the stuff before. (Apparently it’s been dubbed ‘gas station heroin’, so maybe I was one of that day’s lucky 1000. I only knew of it being sold at a lot of smoke shops, but at least you know what you’re buying there.)

      Now, I admit, I didn’t see the bottle myself. Maybe my buddy’s dad is a dumbass (actually, no maybe about it, he certainly is from the stories I’ve heard), maybe the people that buy those supplements from dick pill stand or drink strange elixirs without thinking much about it don’t deserve my sympathy, but in an ideal world that kind of warning would at the very least be really hard to miss before you take it and especially before you get behind the wheel of a car…

    • Junkhead@slrpnk.net
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      1 month ago

      Its crazy how stuff like this is legal and teens used to go to gas stations to buy shit like k2 and saliva.

    • shneancy@lemmy.world
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      1 month ago

      lsd my beloved :( ostracised because they had to put hippies in prison for something. schedule I with no medical uses my ass too, that ban stopped every ongoing research into how lsd could help in psychiatry, and though research wasn’t finished it sure as hell didn’t look like it was useless. The US drug enforcement administration lied in nearly every single part of their statement following the ban

      • Glytch@lemmy.world
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        1 month ago

        Quick LSD anecdote: LSD literally reminded me what actual happiness feels like. I’ve struggled with depression for much of my life and had a stretch of about a decade where my mood never rose above the level of “meh” and was often much worse than that. LSD filled me with joy and allowed me to feel happiness again even after I came back down.

        For that reason I will forever be an LSD advocate.

      • Zoboomafoo@slrpnk.net
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        1 month ago

        US Government: “A substance that makes people more empathetic? This could destroy the American way of life!”

        • shneancy@lemmy.world
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          1 month ago

          bruh you have no idea how correct you are on that

          “By the mid-1960s the backlash against the use of LSD and its perceived corrosive effects on cultural values resulted in governmental action to restrict the availability of the drug by making use of it illegal.[29]”

          now let’s all have a sit down and think about the state of the “cultural values” if feeling love towards your fellow human beings, and jamming to music is somehow corrosive to them… just- i have no idea how people fell for that bullshit

  • t�m@lemmy.ml
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    1 month ago

    Take 50 of them and you’ll be seeing the god you believe in